{"id":64664,"date":"2022-04-14T10:40:59","date_gmt":"2022-04-14T10:40:59","guid":{"rendered":"https:\/\/pr.asianetpakistan.com\/?p=90082"},"modified":"2022-04-14T10:40:59","modified_gmt":"2022-04-14T10:40:59","slug":"international-team-led-by-bgi-completes-first-whole-body-cell-atlas-of-a-non-human-primate","status":"publish","type":"post","link":"https:\/\/kuwaitnewsgazette.com\/international-team-led-by-bgi-completes-first-whole-body-cell-atlas-of-a-non-human-primate\/","title":{"rendered":"International Team Led by BGI Completes First Whole-Body Cell Atlas of a Non-Human Primate"},"content":{"rendered":"
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The research will provide insights into the development of potential treatments for neurological diseases and obesity, among other human conditions.<\/i><\/p>\n

SHENZHEN, China, April 14, 2022 \/PRNewswire\/ — In a breakthrough that could lead to scientific advancement in the treatment of human diseases, researchers from BGI-Research, together with scientific research teams from China, Germany, Italy, Singapore, Spain, Sweden and the UK, today published the world’s first non-human primate whole-body cell transcriptomic atlas in the scientific journal Nature<\/a><\/i>.<\/i><\/p>\n

By using BGI’s independently-developed DNBelab C4 single-cell library platform, the researchers from BGI, Jilin University, Guangzhou Institutes of Biomedicine and Health (Chinese Academy of Sciences), and 32 other international institutions completed the single-cell transcriptome of 45 tissues and organs from long-tailed macaque (cynomolgus) monkeys, obtaining a total of 1.14 million single-cell data and identifying 113 major cell types.\u00a0The study, “Cell transcriptomic atlas of the non-human primate Macaca fascicularis<\/i>“, obtained ethical clearance before it was conducted.<\/p>\n

This study and other large scale primate research at the single-cell level are only possible through developments in advanced sequencing technology, an area where BGI is a leader. BGI’s proprietary technology enables extensive and multi-dimensional single-cell analysis with high sensitivity and accuracy at a low cost.<\/p>\n

“Single-cell research is transforming our understanding of tissue and organ functions at a cellular level, which informs how diseases develop and how they can be treated,” said Dr. Liu Longqi from BGI-Research, one of the corresponding authors of the paper. “Having a whole-body organ single-cell map of the adult macaque will significantly improve the ability to pinpoint how to develop potential treatments for human diseases with greater precision.”<\/p>\n

By mapping the macaque transcriptome at the single-cell level, scientists now have a database, or single-cell library, that can be used for<\/p>\n